Remdesivir drug for Covid 19 – Burning Issues – Free PDF Download

 What is Remdesivir?

• Remdesivir is an experimental antiviral drug that was developed by US pharmaceutical company Gilead Sciences first for Hepatitis C and then as a potential treatment for Ebola.
• The drug was rapidly pushed through clinical trials after the 2013-16 Ebola epidemic in West Africa.

• The drug was one among four therapies, which underwent clinical trials in the Democratic Republic of Congo in 2018.
• Remdesivir wasn’t a successful candidate for Ebola. The other two were better against Ebola Virus.
• 2020 January: Remdesivir made a revival as a treatment for Covid-19 as it had shown promising results in blocking Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS).

April 10: First Study

• Compassionate drug use is the use of a new, unapproved drug to treat a seriously ill patient when no other treatments are available.

Reduces Recovery Time {15 to 11 Days}

•  The patients who were administered the drug, he added, were discharged from the hospital in 11 days, on average, as compared to 15 days.
•  “What it has proven is that a drug can block this virus,” He said the drug would become part of standard Covid19 care in the US.

1-May

•  It is to be used for hospitalized patients with “severe disease,” such as those who need supplemental oxygen or ventilators to breathe.

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• Will it reduce deaths?
•  This part is still under review. Three other trials have been conducted to test the efficacy of remdesivir for Covid-19 treatment.

Are there side effects of Remdesivir?

•  As per the FDA, two possible side effects of remdesivir are as follows:
• Increase in the levels of liver enzymes, indicating that it may negatively affect the liver.
• Infusion-related reaction during the administration of the drug. It shows up as nausea, vomiting, shivering, sweating and low blood pressure.
• Covid-19 has killed over 2.5 lakh people worldwide since it was first reported in December 2019, but a cure and vaccination remain elusive.

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